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Lab for Retinal Cell Biology

Publications 2019

Storti, F., Klee, K., Todorova, V., Steiner, R., Othman, A., van der Velde-Visser, S., Samardzija, M., Meneau, I., Barben, M., Karademir, D., Pauzuolyte, V., Boye, S.L., Blaser, F., Ullmer, C., Dunaief, J.L., Hornemann, T., Rohrer, L., den Hollander, A., von Eckardstein, A., Fingerle, J., Maugeais, C., Grimm, C. (2019)
Impaired ABCA1/ABCG1-mediated lipid efflux in the mouse retinal pigment epithelium (RPE) leads to retinal degeneration.
eLife, 2019 Mar 13;8. pii: e45100

Festa, B.P., Berquezl, M., Gassama, A., Amrein, I., Ismail, H.M., Samardzija, M., Staiano, L., Luciani, A., Grimm, C., Nussbaum, R.L., De Matteis, M.A., Dorchies, O.M., Scapozza, L., Wolfer, D.P., Devuyst, O. (2019)
OCRL deficiency impairs end-lysosomal function in a humanised mouse model for Lowe syndrome and Dent disease.
Hum Mol Genet. 2019, 28(12):1931-1946

Schori, C., Trachsel, C., Grossmann, J., Barben, M., Klee, D., Storti, F., Samardzija, M., Grimm, C. (2019)
A chronic hypoxic response in photoreceptors alters the vitreous proteome in mice.
Exp Eye Res, Aug 185:107690

Hudson, N., Celkova, L., Hopkins, A., Greene, C., Storti, F., Ozaki, E., Fahey, E., Theodoropoulou, S., Kenna, P.F., Humphries, M.M., Curtis, A., Demmons, E., Browne, A., Liddie, S., Lawrence, M.S., Grimm, C., Cahill, M., Humphries, P., Doyle, S.L., Campbell, M. (2019)
Dysregulated claudin-5 cycling in the inner retina causes retinal pigment epithelial cell atrophy.
J Clin. Invest. Insight, Aug 8;4(15). pii: 130273

Samardzija, M., Todorova, V., Gougoulakis, L., Barben, M., Nötzli, S., Klee, K., Storti, F., Gubler, A., Imsand, C., Grimm, C. (2019)
Light stress affects cones and horizontal cells via rhodopsin-mediated mechanisms
Exp Eye Res, Sep 186; 107719

Manogaran, P., Samardzija, M., Schad, A.N., Wicki, C.A., Walker-Egger, D., Rudin, M., Grimm, C., Schippling, S. (2019)
Retinal pathology in experimental optic neuritis is characterised by retrograde degeneration and gliosis.
Acta Neuropathol Commun. 2019, July 17;7(1):116

Klee, K., Storti, F., Barben, M., Samardzija, M., Langmann, T., Dunaief, J., Grimm, C. (2019)
Systemic knockout of Tspo in mice does not affect retinal morphology, function and susceptibility to degeneration.
Exp Eye Res. Sep 25;188:107816

Samardzija, M., Barben, M., Todorova, V., Klee, K., Storti, F., Grimm, C. (2019)
Hif1a and Hif2a can be safely inactivated in cone photoreceptors.
Sci. Rep. 2019 Nov 6;9(1):16121

Grimm, C. Remé, C.E. (2019)
Light damage models of retinal degeneration
Methods Mol Bio. 2nd Edition;1834:167-178

Barben, M., Bordonhos, A., Samardzija, M., Grimm, C. (2019)
Hypoxia-regulated microRNAs in the retina.
Adv. Exp. Med. Biol. 2019;1185:413-417

Storti, F., Grimm, C. (2019)
Active cholesterol efflux in the retina and retinal pigment epithelium.
Adv. Exp. Med. Biol. 2019;1185:51-55

Edited Book:
Retinal Degenerative Diseases. Mechanisms and Experimental Therapy (2019)
Advances in experimental medicine and biology. Volume 1185; Bowes Rickman, C., Grimm, C., Anderson R.E., Ash, J.D., LaVail M.M., Hollyfield J.G., Grimm C. (eds).
Springer Science+Business Media, LLC, New York; ISBN 978-3-030-27377-4