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Publications 2025

Ebner, L.J.A., Karademir, D., Nötzli, S., Wögenstein, G.M., Samardzija, M., Grimm, C. (2025).
Oxygen-dependent alternative mRNA splicing and a cone-specific motor protein revealed by single-cell RNA sequencing in hypoxic retinas
Exp Eye Res. 2025, 14:6578. doi: 10.1038/s41467-023-42386-0
 
Govers, L.P., Grimm, C. (2025).
The connection between cellular metabolism and retinal disease
Adv Exp Med Biol. 2025; 1468:267-271. doi: 10.1007/978-3-031-76550-6_44
 
Wögenstein, G.M., Grimm, C. (2025).
Genetically encoded metabolic sensors to study retina metabolism
Adv Exp Med Biol. 2025;1468:465-469. doi: 10.1007/978-3-031-76550-6_76
 
Merolla, M., Samardzija, M., Kostic, C., Grimm, C. (2025).
Photoreceptor activation drives the expression of the immediate-early gene Egr1 in 
inner retinal neurons
Exp Eye Res. 2025 Aug 26:110602.  doi: 10.1016/j.exer.2025.110602
 
Geiger, F., Heigl, T., Merolla, M., Yong, M., Wögenstein, GM., Govers, L., Tsioti, I., Fottner, A., Samardzija, M., Grimm, C. (2025).
HIF1 activity drives type 3 neovascularization and retinal atrophy in a new mouse model of 
age-related macular degeneration
Cell Death Dis, accepted
 
Ebner, L.J.A., Imsand, C., Karademir, D., Peters, F., Kiessling, E., Fottner, A., Matter, C., Fajardo, D.S., Merolla, L., Wögenstein, G.M., Tsioti, I., Govers, L.P., Blaser, F., Meneau, I., Boye, S.L., Boye, S.E., Grimm, C., Samardzija, M. (2025).
A novel multiplex RNAi therapy simultaneously targets Hif1a and Hif2a to defy retinal degeneration in two models of AMD
Mol Ther, accepted
 
Wögenstein, GM., Ravotto, L., Todorova, V., Meister, RM., Samardzija, M., Weber, B., Grimm, C. 
Biosensor imaging maps aerobic glycolysis to photoreceptors and reveals 
metabolic divergence across retinal layers
submitted