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Publications 2026

Merolla, L., Fottner, A., Imsand, C., Matter, C., Rowlan, J., Neitz, M., Govers, P., Samardzija, M., Grimm, C.
RNA interference to reduce Egr1 expression in rods delays retinal degeneration in 
a model of retinitis pigmentosa
Mol Vis, 2026;32:102-118
 
Ebner, L.J.A., Imsand, C., Karademir, D., Peters, F., Kiessling, E., Fottner, A., Matter, C., Fajardo, D.S., Merolla, L., Wögenstein, G.M., Tsioti, I., Govers, L.P., Blaser, F., Meneau, I., Boye, S.L., Boye, S.E., Grimm, C., Samardzija, M. (2026).
A novel multiplex RNAi therapy simultaneously targets Hif1a and Hif2a to defy retinal degeneration in two models of AMD
Mol Ther, 2026 Jan 07:34(1):348-366  doi: 10.1016/j.ymthe.2025.09.044
 
Wögenstein, GM., Ravotto, L., Todorova, V., Meister, RM., Samardzija, M., Barros, L.-F., Weber, B., Grimm, C. 
Rod photoreceptors have a dual dependency on both aerobic glycolysis and OXPHOS and diverge metabolically from other retinal neurons
Science Adv, 2026, in press
 
Govers, LP., Hass, DT., Agbaga, M-P., Matter, C., Fottner, A., Samardzija, M., Hurley, JB., Grimm, C. 
Chronic Hypoxic Signalling Reprograms Metabolism and Alters Redox and Lipid Homeostasis in Rod Photoreceptors
Submitted
 
Govers, LP., Wögenstein, GM., Merolla, L., Fottner, A., Taverna, SA., Becirovic, E., Samardzija, M., Grimm, C. 
Mitochondrial organization in rod and cone photoreceptors and intercellular mitochondrial material transfer in models of blinding disease
Submitted
 
Yong, M., Govers, LP., Fottner, A., Samardzija, M., Heigl, T., Merolla, L., Meneau, I., Blaser, F., Grimm, C. 
Decoding the Retinal ADAR Landscape
Submitted